发明授权
- 专利标题: Bioengineered tissue substitutes
- 专利标题(中): 生物工程组织替代品
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申请号: US10374755申请日: 2003-02-24
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公开(公告)号: US07622299B2公开(公告)日: 2009-11-24
- 发明人: Joan E. Sanders , Thomas Neumann
- 申请人: Joan E. Sanders , Thomas Neumann
- 申请人地址: US WA Seattle
- 专利权人: University of Washington
- 当前专利权人: University of Washington
- 当前专利权人地址: US WA Seattle
- 代理机构: Christensen O'Connor Johnson Kindness PLLC
- 主分类号: C12N5/06
- IPC分类号: C12N5/06
摘要:
In one aspect, the invention provides methods for forming a target tissue substitute. The methods of the invention comprise the following steps: (a) providing a scaffold comprising one or more layers of one or more arrays of microfibers, wherein one or more of the arrays of microfibers is designed to mimic the configuration of one or more structural elements in a target tissue; and (b) culturing cells on the scaffold to form a target tissue substitute. In another aspect, the invention provides implantable medical devices. The implantable medical devices of the invention comprise a scaffold comprising one or more layers of one or more arrays of microfibers, wherein one or more of the arrays of microfibers is arranged to mimic the configuration of one or more structural elements in a target tissue. Typically, cells are cultured on the scaffold to form a target tissue substitute.
公开/授权文献
- US20030211130A1 Bioengineered tissue substitutes 公开/授权日:2003-11-13