Invention Grant
US07622473B2 'N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites
有权
'N-（2-氯-6-甲基苯基）-2 - [[（6- [4-（2-羟基乙基）-1-哌嗪基] -2-甲基-4-嘧啶基]氨基] -5-噻唑甲酰胺代谢物
!['N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites](/docs/US/2009-11-24/US07622473B2/abs.jpg.600x600.jpg)
- Patent Title: 'N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites
- Patent Title (中): 'N-（2-氯-6-甲基苯基）-2 - [[（6- [4-（2-羟基乙基）-1-哌嗪基] -2-甲基-4-嘧啶基]氨基] -5-噻唑甲酰胺代谢物
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Application No.: US11376665Application Date: 2006-03-15
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Publication No.: US07622473B2Publication Date: 2009-11-24
- Inventor: Vinod Kumar Arora , Lisa Joy Christopher , Donghui Cui , Wenying Li
- Applicant: Vinod Kumar Arora , Lisa Joy Christopher , Donghui Cui , Wenying Li
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Mary K. VanAtten
- Main IPC: A61K31/497
- IPC: A61K31/497 ; C07D403/00
!['N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites](/abs-image/US/2009/11/24/US07622473B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to metabolites of ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, the compound of formula (I), pharmaceutical compositions thereof, and to methods of using the metabolites and the pharmaceutical compositions in the treatment of oncological and immunological disorders.
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