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!['N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites](/abs-image/US/2009/11/24/US07622473B2/abs.jpg.150x150.jpg)
1.发明授权'N-(2-chloro-6-methylphenyl)-2-[[(6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites 有权'N-（2-氯-6-甲基苯基）-2 - [[（6- [4-（2-羟基乙基）-1-哌嗪基] -2-甲基-4-嘧啶基]氨基] -5-噻唑甲酰胺代谢物公开(公告)号：US07622473B2
公开(公告)日：2009-11-24
申请号：US11376665
申请日：2006-03-15
IPC分类号： A61K31/497 , C07D403/00
CPC分类号： C07D417/12 , C07D417/14
摘要： The present invention is directed to metabolites of ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, the compound of formula (I), pharmaceutical compositions thereof, and to methods of using the metabolites and the pharmaceutical compositions in the treatment of oncological and immunological disorders.
摘要翻译： 本发明涉及“N-（2-氯-6-甲基苯基）-2 - [[6- [4-（2-羟乙基）-1-哌嗪基] -2-甲基-4-嘧啶基]氨基 ] -5-噻唑甲酰胺，式（I）化合物，其药物组合物，以及使用代谢物和药物组合物治疗肿瘤学和免疫学疾病的方法。
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公开(公告)号：US20220306465A1
公开(公告)日：2022-09-29
申请号：US17702721
申请日：2022-03-23
申请人： Vinod Kumar Arora
发明人： Vinod Kumar Arora
摘要： This disclosure relates installed or new synthesis gas (Syngas) production units and potential modifications to those units to reduce the firing requirements and significant emissions of CO2 from those units with affordable capital expenditures.
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公开(公告)号：US11131486B2
公开(公告)日：2021-09-28
申请号：US16380127
申请日：2019-04-10
申请人： Vinod Kumar Arora
发明人： Vinod Kumar Arora
摘要： An improved performance ammonia plant system utilizing both a direct and indirect chilling of the compressed process air train using a single or multistage chilling system integrated with the ammonia plant ammonia compression train to increase process air flow to the secondary ammonia reformer of the ammonia plant.
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![(R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol metabolites](/abs-image/US/2014/07/15/US08778893B2/abs.jpg.150x150.jpg)
4.发明授权(R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol metabolites 有权（R）-1-（4-（4-氟-2-甲基-1H-吲哚-5-基氧基）-5-甲基吡咯并[2,1-f] [1,2,4]三嗪-6-基氧基） 丙-2-醇代谢物公开(公告)号：US08778893B2
公开(公告)日：2014-07-15
申请号：US13500365
申请日：2010-10-04
IPC分类号： C07H15/26 , C07D487/04
CPC分类号： C07D487/04 , C07H15/26
摘要： The present invention is directed to metabolites of (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol, the compound of formula (I), pharmaceutical compositions thereof, and to methods of using the metabolites and the pharmaceutical compositions in the treatment of cancer.
摘要翻译： 本发明涉及（R）-1-（4-（4-氟-2-甲基-1H-吲哚-5-基氧基）-5-甲基吡咯并[2,1-f] [1,2， 4]三嗪-6-基氧基）丙-2-醇，式（I）化合物，其药物组合物，以及使用代谢物和药物组合物治疗癌症的方法。
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5.发明申请TASTE MASKED DOSAGE FORMS OF BITTER TASTING ANTI-RETROVIRAL DRUGS 审中-公开叮TE。。。。。。。。。。。。。。。。。。。。。。。。。公开(公告)号：US20130177520A1
公开(公告)日：2013-07-11
申请号：US13519025
申请日：2010-12-23
IPC分类号： A61K47/48
CPC分类号： A61K47/585 , A61K9/205 , A61K9/2054 , A61K31/427 , A61K31/4418 , A61K31/495 , A61K31/513 , A61K31/52
摘要： The present invention relates to taste masked dosage forms of bitter tasting anti-retroviral drugs comprising a complex of the said anti-retroviral drug and an ion-exchange resin and one or more of other pharmaceutically acceptable excipients. It further relates to the processes for the preparation thereof.
摘要翻译： 本发明涉及苦味抗逆转录病毒药物的掩味剂，其包含所述抗逆转录病毒药物和离子交换树脂与一种或多种其它可药用赋形剂的复合物。 它还涉及其制备方法。
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公开(公告)号：US20190264959A1
公开(公告)日：2019-08-29
申请号：US16380127
申请日：2019-04-10
申请人： Vinod Kumar Arora
发明人： Vinod Kumar Arora
摘要： An improved performance ammonia plant system utilizing both a direct and indirect chilling of the compressed process air train using a single or multistage chilling system integrated with the ammonia plant ammonia compression train to increase process air flow to the secondary ammonia reformer of the ammonia plant.
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公开(公告)号：US10302337B2
公开(公告)日：2019-05-28
申请号：US15682974
申请日：2017-08-22
申请人： Vinod Kumar Arora
发明人： Vinod Kumar Arora
摘要： An ammonia plant system upgrade utilizing both a direct and indirect multistage chilling system in the ammonia plant air compression train to increase process air flow to the secondary ammonia reformer of an ammonia plant as well as upgrades to provide more pre-heating along with increased process air flow.
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公开(公告)号：US10302338B2
公开(公告)日：2019-05-28
申请号：US15683026
申请日：2017-08-22
申请人： Vinod Kumar Arora
发明人： Vinod Kumar Arora
摘要： An ammonia plant system upgrade utilizing both a direct and indirect multistage chilling system in the ammonia plant air compression train to increase process air flow to the secondary ammonia reformer of an ammonia plant as well as upgrades to provide more pre-heating along with increased process air flow.
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公开(公告)号：US09463163B2
公开(公告)日：2016-10-11
申请号：US13502194
申请日：2010-10-18
IPC分类号： A61K9/30 , A61K9/20 , A61K9/28 , A61K31/195 , A61K9/48
CPC分类号： A61K9/2054 , A61K9/2846 , A61K9/4808 , A61K9/4866 , A61K31/195
摘要： The invention relates to a delayed release pharmaceutical composition of mesalamine comprising: a) granules comprising mesalamine or pharmaceutically acceptable salts thereof and a hydrophilic polymer; b) extragranular excipients; wherein the pharmaceutical composition is further coated with a single layer of polymer.
摘要翻译： 本发明涉及美沙拉嗪的延迟释放药物组合物，其包含：a）包含美沙拉嗪或其药学上可接受的盐和亲水性聚合物的颗粒; b）颗粒外赋形剂; 其中所述药物组合物进一步用单层聚合物涂覆。
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公开(公告)号：US09107929B2
公开(公告)日：2015-08-18
申请号：US12434499
申请日：2009-05-01
CPC分类号： A61K31/65 , A61K9/0019 , A61K9/08 , A61K9/19
摘要： The invention relates to stable parenteral formulations of tigecycline and process of preparation thereof, wherein the formulation comprises an edetate, a pH modifying agent or an antioxidant, such that the formulation remains stable for at least 45 hours.
摘要翻译： 本发明涉及替加环素的稳定胃肠外制剂及其制备方法，其中所述制剂包含依地酸盐，pH调节剂或抗氧化剂，使得制剂保持稳定至少45小时。
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