发明授权
- 专利标题： Modulators of PPAR and methods of their preparation
- 专利标题（中）： PPAR的调节剂及其制备方法
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申请号： US11202963申请日： 2005-08-11
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公开(公告)号： US07622491B2公开(公告)日： 2009-11-24
- 发明人: Yan Zhu , Jingyuan Ma , Peng Cheng , Zuchun Zhao , Francine M. Gregoire , Vera A. Rakhmanova
- 申请人： Yan Zhu , Jingyuan Ma , Peng Cheng , Zuchun Zhao , Francine M. Gregoire , Vera A. Rakhmanova
- 申请人地址： US CA Hayward
- 专利权人： Metabolex Inc.
- 当前专利权人： Metabolex Inc.
- 当前专利权人地址： US CA Hayward
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/415 ; C07D207/00 ; C07D231/00 ; C07D233/00
摘要：
The present invention is directed to certain novel compounds represented by Formula (I) and pharmaceutically acceptable salts, solvates, hydrates and prodrugs thereof. The present invention is also directed to methods of making and using such compounds and pharmaceutical compositions containing such compounds to treat or control a number of diseases mediated by PPAR such as glucose metabolism, lipid metabolism and insulin secretion, specifically Type 2 diabetes, hyperinsulinemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for cardiovascular disease, Syndrome X, hypertriglyceridemia, hyperglycemia, obesity and eating disorders.
公开/授权文献
- US20060058301A1 Modulators of PPAR and methods of their preparation 公开/授权日：2006-03-16
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