发明授权
- 专利标题: Chemokine receptor binding heterocyclic compounds
- 专利标题(中): 趋化因子受体结合杂环化合物
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申请号: US11494943申请日: 2006-07-27
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公开(公告)号: US07629337B2公开(公告)日: 2009-12-08
- 发明人: Gary J. Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor R. Wilson , Jason Crawford , Ernest J. McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
- 申请人: Gary J. Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor R. Wilson , Jason Crawford , Ernest J. McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
- 申请人地址: US MA Cambridge
- 专利权人: Genzyme Corporation
- 当前专利权人: Genzyme Corporation
- 当前专利权人地址: US MA Cambridge
- 代理机构: Morrison & Foerster LLP
- 主分类号: C07D213/16
- IPC分类号: C07D213/16 ; C07D213/22 ; A61K31/44 ; A61K31/4427 ; A61P19/02 ; A61P31/18
摘要:
Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor.
公开/授权文献
- US20060264434A1 Chemokine receptor binding heterocyclic compounds 公开/授权日:2006-11-23
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