发明授权
US07632828B2 Gram-positive carbapenem antibacterials and processes for their preparation
失效
革兰氏阳性碳青霉烯类抗生素及其制备方法
- 专利标题： Gram-positive carbapenem antibacterials and processes for their preparation
- 专利标题（中）： 革兰氏阳性碳青霉烯类抗生素及其制备方法
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申请号： US11150522申请日： 2005-06-10
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公开(公告)号： US07632828B2公开(公告)日： 2009-12-15
- 发明人: Woo-Baeg Choi , David S. Menaldino , Deog-Il Kim , Martin Bouygues , Michael W. Hager
- 申请人： Woo-Baeg Choi , David S. Menaldino , Deog-Il Kim , Martin Bouygues , Michael W. Hager
- 申请人地址： US GA Kennesaw
- 专利权人： FOB Synthesis, Inc.
- 当前专利权人： FOB Synthesis, Inc.
- 当前专利权人地址： US GA Kennesaw
- 代理机构： King & Spalding
- 主分类号： C07D477/12
- IPC分类号： C07D477/12 ; A61K31/407 ; A61P31/04 ; A61K31/5377 ; A61K31/426 ; A61K31/4439 ; A61K31/4995 ; A61K31/496 ; A61K31/4178
摘要：
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ÿ-methyl carbapenems which are useful as antibacterial agents.
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