发明授权
- 专利标题： Factor VIII/vWF-complex and methods of purifying same
- 专利标题（中）： 因子VIII / vWF-复合物及其纯化方法
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申请号： US10789562申请日： 2004-02-27
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公开(公告)号： US07648958B2公开(公告)日： 2010-01-19
- 发明人: Artur Mitterer , Bernhard Fischer , Oyvind L. Schönberger , Kathrin Thomas-Urban , Friedrich Dorner , Johann Eibl
- 申请人： Artur Mitterer , Bernhard Fischer , Oyvind L. Schönberger , Kathrin Thomas-Urban , Friedrich Dorner , Johann Eibl
- 申请人地址： AT Vienna
- 专利权人： Baxter Innovations GmbH
- 当前专利权人： Baxter Innovations GmbH
- 当前专利权人地址： AT Vienna
- 代理机构： Townsend and Townsend and Crew LLP
- 优先权： AU338/97 19970227
- 主分类号： A01N37/18
- IPC分类号： A01N37/18
摘要：
There is disclosed a method of recovering factor VIII/vWF-complex which is characterized in that factor VIII/vWF-complex from a protein solution is bound to a cation exchanger and is recovered by step-wise elution of factor VIII/vWF-complex, which particularly contains high-molecular vWF multimers, as well as a factor VIII/vWF-complex obtainable by means of cation exchange chromatography.
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