发明授权
- 专利标题： Azabicyclic aryl derivatives and their medical use
- 专利标题（中）： 氮杂芳基衍生物及其医疗用途
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申请号： US11663152申请日： 2005-10-14
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公开(公告)号： US07652010B2公开(公告)日： 2010-01-26
- 发明人: Dan Peters , Daniel B. Timmermann , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen
- 申请人： Dan Peters , Daniel B. Timmermann , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen
- 申请人地址： DK Ballerup
- 专利权人： Neurosearch A/S
- 当前专利权人： Neurosearch A/S
- 当前专利权人地址： DK Ballerup
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： DKPA200401582 20041015
- 国际申请： PCT/EP2005/055263 WO 20051014
- 国际公布： WO2006/040352 WO 20060420
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/501 ; A61K31/53 ; A61K31/497 ; A61K31/506 ; C07D401/04 ; C07D498/08 ; C07D513/08 ; C07D515/08 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; A61K43/66 ; A61P29/00 ; C07D453/02
摘要：
Azabicyclo pyridazinyl compounds including azabicyclooctyl-pyridazinyl-oxy compounds, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile, the compounds may be used for the treatment of various diseases or disorders, including those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
公开/授权文献
- US20070299082A1 Novel Azabicyclic Aryl Derivatives and Their Medical Use 公开/授权日：2007-12-27
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