发明授权
- 专利标题： Methods for converting quinolone esters into quinolone amides
- 专利标题（中）： 将喹诺酮酯转化成喹诺酮酰胺的方法
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申请号： US11149007申请日： 2005-06-09
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公开(公告)号： US07652134B2公开(公告)日： 2010-01-26
- 发明人: Jeffrey P. Whitten , Fabrice Pierre , Collin Regan , Michael Schwaebe , George Petros Yiannikouros , Michael Jung
- 申请人： Jeffrey P. Whitten , Fabrice Pierre , Collin Regan , Michael Schwaebe , George Petros Yiannikouros , Michael Jung
- 申请人地址： US CA San Diego
- 专利权人： Cylene Pharmaceuticals, Inc.
- 当前专利权人： Cylene Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Morrison & Foerster LLP
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D401/14
摘要：
The present invention relates to methods of preparing compounds having formula (1), (2), (5), and ((6A)-(6D)) comprising contacting the corresponding ester, an amine with formula NHR1R2, and a Lewis acid having formula MLn, wherein L is a halogen atom or an organic radical, n is 3-5, and M is a group III elemental atom, a group IV elemental atom, As, Sb, V or Fe, wherein A, B, V, X, Z, W, R1, R2, R5, Z1, Z2, Z3, Z4, Z5, Z6, Z7, and Z8 are substituents. Z4, Z5, Z6, Z7, and Z8 are substituents.
公开/授权文献
- US20060063761A1 Novel benzothiazole compounds and methods of use thereof 公开/授权日：2006-03-23
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