发明授权
US07659267B2 1,3-Benzothiazinone derivatives, process for producing the same use thereof
失效
1,3-苯并噻嗪酮衍生物，其制备方法相同
- 专利标题： 1,3-Benzothiazinone derivatives, process for producing the same use thereof
- 专利标题（中）： 1,3-苯并噻嗪酮衍生物，其制备方法相同
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申请号： US10537520申请日： 2003-12-04
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公开(公告)号： US07659267B2公开(公告)日： 2010-02-09
- 发明人: Masahiro Kajino , Yutaka Nakayama , Haruhide Kimura
- 申请人： Masahiro Kajino , Yutaka Nakayama , Haruhide Kimura
- 申请人地址： JP Osaka-Shi
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Osaka-Shi
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 代理商 David G. Conlin; Dwight D. Kim
- 优先权： JP2002-353546 20021205
- 国际申请： PCT/JP03/15535 WO 20031204
- 国际公布： WO2004/060881 WO 20040722
- 主分类号： C07D279/16
- IPC分类号： C07D279/16 ; A61K31/5415
摘要：
As prophylactic and/or therapeutic agents for cardiovascular diseases, bone or joint diseases, infectious diseases, inflammatory diseases, kidney diseases, etc. having safe and excellent effects of cell death inhibition, MIF binding, etc., there are provided compounds represented by formula: [wherein, R1 represents a halogen atom, etc., R2 represents a group represented by formula: (wherein, R3 represents hydrogen atom, an optionally substituted alkoxy, etc., R4 represents hydrogen atom, bromine atom, cyano, etc., R5 represents hydrogen atom, hydroxy, etc., R6 represents hydrogen atom, etc., R7 represents hydrogen atom, etc.) etc., and n represents an integer of 0 to 4] or salts thereof.
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