发明授权
- 专利标题: HMG-CoA reductase inhibitors
- 专利标题(中): HMG-CoA还原酶抑制剂
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申请号: US11789335申请日: 2007-04-24
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公开(公告)号: US07659281B2公开(公告)日: 2010-02-09
- 发明人: Philip D. Stein , Steven P. Seitz , David J. Carini , Yan Shi , Jeffrey A. Robl , Jay A. Markwalder , Chunhong He
- 申请人: Philip D. Stein , Steven P. Seitz , David J. Carini , Yan Shi , Jeffrey A. Robl , Jay A. Markwalder , Chunhong He
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理商 Burton Rodney
- 主分类号: A01N43/42
- IPC分类号: A01N43/42 ; A61K31/44 ; C07D221/18 ; C07D221/22
摘要:
Compounds are provided of the following structure are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia and dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis wherein variables A and B are defined herein.
公开/授权文献
- US20070249583A1 HMG-CoA reductase inhibitors 公开/授权日:2007-10-25
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