Invention Grant
US07662374B2 Monoclonal antibodies to activated erbB family members and methods of use thereof
有权
活化的erbB家族成员的单克隆抗体及其使用方法
- Patent Title: Monoclonal antibodies to activated erbB family members and methods of use thereof
- Patent Title (中): 活化的erbB家族成员的单克隆抗体及其使用方法
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Application No.: US10213292Application Date: 2002-08-05
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Publication No.: US07662374B2Publication Date: 2010-02-16
- Inventor: Mark I. Greene , Hongtao Zhang , Mark Richter , Ramachandran Murali
- Applicant: Mark I. Greene , Hongtao Zhang , Mark Richter , Ramachandran Murali
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of The University of Pennsylvania
- Current Assignee: The Trustees of The University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Woodcock Washburn, LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12P21/08 ; C07K16/28 ; G01N33/53 ; G01N33/534 ; G01N33/574
Abstract:
Antibodies which bind to activated members of the erbB, TNF, and IgSF family of receptors and pharmaceutical compositions comprising the same are disclosed. Peptides and mimetics of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are also described. Methods of using such antibodies, peptides, and mimetics in tumor therapeutic, prophylactic, imaging and diagnostic applications are disclosed.
Public/Granted literature
- US20060073140A1 Monoclonal antibodies to activated erbB family members and methods of use thereof Public/Granted day:2006-04-06
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