发明授权
- 专利标题: ZAQ ligand-1 antibodies and uses thereof
- 专利标题(中): ZAQ配体-1抗体及其用途
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申请号: US10542664申请日: 2004-01-21
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公开(公告)号: US07662380B2公开(公告)日: 2010-02-16
- 发明人: Hirokazu Matsumoto , Yasuko Horikoshi , Yasushi Masuda , Tetsuya Ohtaki
- 申请人: Hirokazu Matsumoto , Yasuko Horikoshi , Yasushi Masuda , Tetsuya Ohtaki
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Foley & Lardner LLP
- 优先权: JP2003-014055 20030122
- 国际申请: PCT/JP2004/000498 WO 20040121
- 国际公布: WO2004/065419 WO 20040805
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12N5/12
摘要:
The antibody of the present invention has an extremely high binding ability to human ZAQL-1, can neutralize the activity of human ZAQL-1, and inhibits the action of human ZAQL-1. Therefore, the antibody is useful as a preventive or therapeutic agent or a diagnostic agent for, e.g., digestive diseases, diseases associated with angiogenesis, diseases relating to pregnancy, eating disorders, sleeping disorders, seasonal depression, reproductive dysfunction, endocrine diseases, senile dementia, Alzheimer's disease, various disorders caused by aging, cerebral circulatory disorders, head trauma, spinal injury, epilepsy, anxiety, depression, manic depression, schizophrenia, alcoholism, Parkinson's disease, hypertension, arteriosclerosis, arrhythmia, premenstral syndrome, glaucoma, cancer, AIDS, diabetes, etc.
公开/授权文献
- US20060217536A1 Antibody and use thereof 公开/授权日:2006-09-28
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