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公开(公告)号：US20120015868A1
公开(公告)日：2012-01-19
申请号：US13135230
申请日：2011-06-29
申请人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto , Jiro Noguchi , Hisanori Matsui
发明人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto , Jiro Noguchi , Hisanori Matsui
IPC分类号： A61K38/08 , A61P3/10 , A61P25/28 , A61P15/00 , A61P35/00 , A61P25/00 , A61P3/04 , A61P13/00 , C07K7/06 , A61P9/10
摘要： The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivitives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.
摘要翻译： 本发明提供了一种转氨酶衍生物，其中包含转氨酶的氨基酸被替代的化学取代基修饰，导致转移衍生物，具有优异的血液稳定性和显示出癌转移抑制作用或癌生长抑制作用。
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公开(公告)号：US07886181B2
公开(公告)日：2011-02-08
申请号：US12041059
申请日：2008-03-03
IPC分类号： G06F11/00
CPC分类号： G06F11/2025 , G06F11/0709 , G06F11/0793 , G06F11/1438 , G06F11/2041 , G06F11/2043
摘要： There is provided a method executed in a cluster system comprising a first computer and at least one second computer that stores the data transmitted from the first computer. The method comprising the steps of: judging whether the failure-occurred processing is restarted by the first computer or the failure-occurred processing is switched over by the second computer based on the system information; receiving the stored data from the second computer and re-executing the processing in which the failure has occurred by the first computer, in the case of which it is judged that the processing in which the failure has occurred is restarted by the first computer; and executing, by the second computer, the processing in which the failure has occurred, in the case of which it is judged that the processing in which the failure has occurred is switched over by the at least one second computer.
摘要翻译： 提供了一种在包括第一计算机和存储从第一计算机发送的数据的至少一个第二计算机的集群系统中执行的方法。 该方法包括以下步骤：基于系统信息，判断第一计算机重新启动故障发生处理或由第二计算机切换故障发生处理; 从所述第二计算机接收所述存储的数据并重新执行由所述第一计算机发生所述故障的处理，在判断已经发生所述故障的处理由所述第一计算机重新启动的情况下; 并且由所述第二计算机执行在所述至少一个第二计算机切换已经发生故障的处理的情况下发生故障的处理。
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公开(公告)号：US20100297855A1
公开(公告)日：2010-11-25
申请号：US12770290
申请日：2010-04-29
IPC分类号： H01L21/302
CPC分类号： H01L21/67092 , B23K26/032 , B23K26/0622 , B23K26/0648 , B23K26/073 , B23K26/082 , B23K26/0853 , B23K26/0876 , B23K26/364 , B23K26/40 , B23K2101/40 , B23K2103/50 , H01L21/78
摘要： A device processing method for improving the die strength of a device divided from a semiconductor wafer. The device processing method includes a chamfering step of applying a pulsed laser beam having an absorption wavelength to the device along the periphery of the device to thereby chamfer the periphery of the device, wherein the pulse width of the pulsed laser beam to be applied in the chamfering step is set to 2 ns or less, and the peak energy density is set in the range of 5 to 200 GW/cm2.
摘要翻译： 一种用于提高从半导体晶片划分的器件的裸片强度的器件处理方法。 该装置处理方法包括：倒角步骤，沿着装置的周边向器件施加具有吸收波长的脉冲激光束，从而使装置的周边倒角，其中施加在该装置中的脉冲激光束的脉冲宽度 倒角步长设定为2ns以下，峰值能量密度设定在5〜200GW / cm 2的范围。
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公开(公告)号：US20100297830A1
公开(公告)日：2010-11-25
申请号：US12771749
申请日：2010-04-30
IPC分类号： H01L21/268
CPC分类号： H01L21/78 , B23K26/0006 , B23K26/0626 , B23K26/40 , B23K2103/50 , B23K2103/56 , H01L21/67132 , H01L21/67144 , H01L21/6836 , H01L2221/68327 , H01L2221/68336
摘要： A laser processing method for a semiconductor wafer including a groove forming step of applying a pulsed laser beam having an absorption wavelength to the semiconductor wafer along a division line formed on the semiconductor wafer to thereby form a laser processed groove along the division lines on the semiconductor wafer, wherein the pulse width of the pulsed laser beam to be applied in the groove forming step is set to 2 ns or less, and the peak energy density is set in the range of 5 to 200 GW/cm2.
摘要翻译： 一种半导体晶片的激光加工方法，包括：槽形成工序，沿着形成在半导体晶片上的分割线，向半导体晶片施加具有吸收波长的脉冲激光束，从而沿着半导体上的分割线形成激光加工槽 晶片，其中在槽形成步骤中施加的脉冲激光束的脉冲宽度设定为2ns以下，峰值能量密度设定在5〜200GW / cm 2的范围内。
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公开(公告)号：US07696067B2
公开(公告)日：2010-04-13
申请号：US12354542
申请日：2009-01-15
IPC分类号： H01L21/30
CPC分类号： H01L21/67092 , B23K26/0853 , B23K26/364 , B23K26/40 , B23K2101/40 , B23K2103/50 , H01L21/3065 , H01L21/67132 , H01L21/78
摘要： A method of manufacturing a device includes: a laser beam-machined groove forming step of irradiating a wafer with a laser beam from the back side of the wafer along planned dividing lines so as to form laser beam-machined grooves along the planned dividing lines; an etching step of etching a back-side surface of the wafer having been subjected to the laser beam-machined groove forming step, so as to remove denatured layers formed at processed surfaces of the laser beam-machined grooves; an adhesive film attaching step of attaching an adhesive film to the back-side surface of the wafer having been subjected to the etching step, and adhering the adhesive film side of the wafer to a surface of a dicing tape; and an adhesive film rupturing step of expanding the dicing tape so as to rupture the adhesive film along individual devices.
摘要翻译： 一种制造装置的方法包括：激光束加工槽形成步骤，沿着预定分割线从晶片的背面用激光束照射晶片，以沿着预定的分割线形成激光束加工的凹槽; 蚀刻步骤，蚀刻已经经过激光加工槽形成步骤的晶片的背面，以去除在激光加工槽的加工表面形成的变性层; 粘合剂膜附着工序，将粘接膜附着在已经进行了蚀刻工序的晶片的背面，并将晶片的粘合膜侧粘接在切割带的表面上; 以及将切割带扩张以使粘合膜沿着各个装置破裂的粘合膜破裂步骤。
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公开(公告)号：US07323541B2
公开(公告)日：2008-01-29
申请号：US10489537
申请日：2002-09-13
申请人： Masaaki Mori , Kozo Hayashi , Hiroyuki Miya , Shuji Sato , Chieko Kitada , Hirokazu Matsumoto , Toshimi Nagi , Yukio Shimomura
发明人： Masaaki Mori , Kozo Hayashi , Hiroyuki Miya , Shuji Sato , Chieko Kitada , Hirokazu Matsumoto , Toshimi Nagi , Yukio Shimomura
IPC分类号： A61K38/04
CPC分类号： C07K14/705 , A61K38/00 , A61K48/00
摘要： The present invention aims at providing a novel polypeptide, a receptor, a DNA thereof, and the like. Specifically, the present invention provides a polypeptide having a binding ability to the protein represented by SEQ ID NO: 1 or SEQ ID NO: 3, or its amide, its ester or its salt, a polynucleotide encoding the polypeptide, an antisense polynucleotide or an antibody to the polypeptide, a screening of agent for prevention and/or treatment of cancer, obesity, etc., which comprises using the above, and the like.The polypeptide, receptor, polynucleotide, antisense polynucleotide, antibody and the like are useful for an agent of prevention and/or treatment of cancer, obesity and the like. Further, they are useful for a screening of an agent for prevention and/or treatment of cancer, obesity and the like.
摘要翻译： 本发明的目的在于提供新的多肽，受体及其DNA等。 具体地说，本发明提供了具有与SEQ ID NO：1或SEQ ID NO：3所代表的蛋白结合能力的多肽或其酰胺，其酯或其盐，编码多肽的多核苷酸，反义多核苷酸或 对多肽的抗体，筛选用于预防和/或治疗癌症，肥胖症等的药剂，其包括使用上述方法等。 多肽，受体，多核苷酸，反义多核苷酸，抗体等可用于预防和/或治疗癌症，肥胖症等。 此外，它们可用于筛选用于预防和/或治疗癌症，肥胖症等的药剂。
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公开(公告)号：US20050209151A1
公开(公告)日：2005-09-22
申请号：US11116727
申请日：2005-04-28
申请人： Chieko Kitada , Hirokazu Matsumoto , Shuji Hinuma
发明人： Chieko Kitada , Hirokazu Matsumoto , Shuji Hinuma
CPC分类号： A61K38/1709
摘要： The ligand polypeptides of the present invention have activity to regulate CRH secretion, and thus are useful as CRH secretion regulators for the relief, prevention or treatment of various diseases related to CRH secretion, such as hypoaldosteronism, hypocortisolemia, secondary and chronic adrenocorticism, Addison's disease (weakness, nausea, pigmentation, hypogonadism, alopecia, hypotension), adrenal dysfunction, and obesity, and also as analgesics.
摘要翻译： 本发明的配体多肽具有调节CRH分泌的活性，因此可用作CRH分泌调节剂用于缓解，预防或治疗与CRH分泌有关的各种疾病，例如醛糖醛酸降低症，低皮质醇血症，继发性和慢性肾上腺皮质激素，艾迪生病 （虚弱，恶心，色素沉着，性腺机能减退，脱发，低血压），肾上腺功能障碍和肥胖，以及止痛药。
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公开(公告)号：US08982332B2
公开(公告)日：2015-03-17
申请号：US13518727
申请日：2011-01-28
申请人： Takehiro Tachizaki , Masahiro Watanabe , Tatsuo Hariyama , Yasuhiro Yoshitake , Tetsuya Matsui , Hirokazu Matsumoto , Kiyoshi Takamasu
发明人： Takehiro Tachizaki , Masahiro Watanabe , Tatsuo Hariyama , Yasuhiro Yoshitake , Tetsuya Matsui , Hirokazu Matsumoto , Kiyoshi Takamasu
CPC分类号： G01S17/36 , G01B9/02003 , G01B9/02007 , G01B9/02008 , G01B9/0207 , G01S7/4815 , G01S7/4911 , G01S17/42
摘要： Disclosed is a distance measuring device using an optical comb. In order for the absolute distance to an object to be measured which has a surface with low reflection ratio or a scattering surface and is approximately 10 m apart, to be easily measured with accuracy of 0.1 mm or more using an optical and contactless method, the distance measuring device which measures the distance to the object to be measured is configured such that the distance to the object to be measured is measured by comparing the phase of the beat signal between a light source and a plurality of CW lasers which are reflected or scattered by the object with the phase of the beat signal between the light source and a plurality of CW lasers prior to being irradiated onto the object.
摘要翻译： 公开了使用光梳的距离测量装置。 为了使具有低反射率或散射面的表面的测量对象的绝对距离相差10微米，使用光学和非接触方法可以容易地测量精度为0.1mm以上， 测量到被测量物体的距离的距离测量装置被配置为通过比较反射或散射的光源和多个CW激光器之间的拍频信号的相位来测量到被测量物体的距离 在被照射到物体上之前，通过光源和多个CW激光器之间的拍频信号的相位的对象。
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公开(公告)号：US20130109744A1
公开(公告)日：2013-05-02
申请号：US13808364
申请日：2011-07-07
IPC分类号： C07H21/02
CPC分类号： C07H21/02 , A61K31/7088 , A61K31/7105 , C12N15/113 , C12N2310/141 , C12Q1/6883 , C12Q2600/158 , C12Q2600/178
摘要： The present invention provides a prophylactic or therapeutic drug for diabetes, which contains a polynucleotide such as miR-199b* and the like. Moreover, the present invention provides a method for screening for a prophylactic or therapeutic drug for diabetes, which includes measuring an expression level of a polynucleotide such as miR-199b* and the like. Furthermore, the present invention provides a method for determining the susceptibility to a prophylactic or therapeutic drug for diabetes, which includes measuring an expression level of a polynucleotide such as miR-199b* and the like.
摘要翻译： 本发明提供了含有miR-199b *等多核苷酸的糖尿病用预防或治疗药物。 此外，本发明提供了用于筛选糖尿病的预防或治疗药物的方法，其包括测量多核苷酸诸如miR-199b *等的表达水平。 此外，本发明提供了测定糖尿病预防或治疗药物的易感性的方法，其包括测定miR-199b *等多核苷酸的表达量。
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公开(公告)号：US08361968B2
公开(公告)日：2013-01-29
申请号：US13135230
申请日：2011-06-29
申请人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto
发明人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto
摘要： The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivitives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.
摘要翻译： 本发明提供了一种转氨酶衍生物，其中包含转氨酶的氨基酸被替代的化学取代基修饰，导致转移衍生物，具有优异的血液稳定性和显示出癌转移抑制作用或癌生长抑制作用。
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