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US07662990B2 Process for preparing ibandronate 有权
伊班膦酸钠的制备方法

  • Patent Title: Process for preparing ibandronate
  • Patent Title (中): 伊班膦酸钠的制备方法
  • Application No.: US12060314
    Application Date: 2008-04-01
  • Publication No.: US07662990B2
    Publication Date: 2010-02-16
  • Inventor: Bernd Junghans
  • Applicant: Bernd Junghans
  • Applicant Address: US NJ Nutley
  • Assignee: Hoffmann-La Roche Inc.
  • Current Assignee: Hoffmann-La Roche Inc.
  • Current Assignee Address: US NJ Nutley
  • Agent George W. Johnston; Patricia S. Rocha-Tramaloni; David E. Wildman
  • Priority: EP07105915 20070411
  • Main IPC: C07F9/38
  • IPC: C07F9/38
Process for preparing ibandronate
Abstract:
The invention relates to a novel multi step synthesis of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid, monosodium salt, monohydrate, of the formula
Abstract(Chinese):

本发明涉及一种新型的多步合成3-（N-甲基-N-戊基）氨基-1-羟基丙烷-1,1-二膦酸，一水合盐，一水合物，式

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