发明授权
- 专利标题: Salts of trimebutine and N-desmethyl trimebutine
- 专利标题(中): 曲美布汀和N-去甲基三苯妥丁的盐
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申请号: US11759154申请日: 2007-06-06
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公开(公告)号: US07666907B2公开(公告)日: 2010-02-23
- 发明人: John Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- 申请人: John Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- 申请人地址: CA Calgary
- 专利权人: Antibe Therapeutics Inc.
- 当前专利权人: Antibe Therapeutics Inc.
- 当前专利权人地址: CA Calgary
- 代理机构: Bennett Jones LLP
- 主分类号: A01N37/44
- IPC分类号: A01N37/44 ; C07C279/00
摘要:
Unique salts of trimebutine and N-monodesmethyl trimebutine, and their corresponding stereoisomers, having improved analgesic properties useful in the treatment of visceral pain are provided. The salts of the present invention are particularly useful in the treatment of conditions characterized by abdominal pain, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), diabetic gastroparesis, and dyspepsia.
公开/授权文献
- US20070275905A1 SALTS OF TRIMEBUTINE AND N-DESMETHYL TRIMEBUTINE 公开/授权日:2007-11-29
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