发明授权
- 专利标题: Pharmaceutical raw material
- 专利标题(中): 制药原料
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申请号: US11451597申请日: 2006-06-13
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公开(公告)号: US07670676B2公开(公告)日: 2010-03-02
- 发明人: Nanao Horiishi , Toshiyuki Hakata , Hirofumi Kawasaki , Shinji Uemoto , Hiromitsu Misawa , Seiichi Takahashi
- 申请人: Nanao Horiishi , Toshiyuki Hakata , Hirofumi Kawasaki , Shinji Uemoto , Hiromitsu Misawa , Seiichi Takahashi
- 申请人地址: JP Hiroshima-shi, Hiroshima-ken
- 专利权人: Toda Kogyo Corporation
- 当前专利权人: Toda Kogyo Corporation
- 当前专利权人地址: JP Hiroshima-shi, Hiroshima-ken
- 代理机构: Nixon & Vanderhye P.C.
- 优先权: JP2005-175801 20050615; JP2005-175802 20050615
- 主分类号: B32B19/00
- IPC分类号: B32B19/00 ; B32B5/16
摘要:
There are provided a pharmaceutical raw material capable of exhibiting a uniform functionality and producing magnetic particle-containing drugs for diagnosis and medical treatments with a high reproducibility. The pharmaceutical raw material comprises a monodisperse colloid sterile aqueous solution of magnetic iron oxide fine particles having an average particle diameter of 5 to 30 nm, a saturation magnetization of 50 to 90 Am2/kg and a coercive force of 0.1 to 1.6 kA/m. The pharmaceutical raw material can be produced by forming magnetic iron oxide fine particles in the form of a colloid aqueous solution, purifying the resultant colloid aqueous solution of superparamagnetic iron oxide particles by water-washing and removing water-soluble salts by-produced upon the reaction from the reaction solution by an ordinary method, and replacing a dispersing medium of the purified colloid aqueous solution with ultrapure water.
公开/授权文献
- US20060287404A1 Pharmaceutical raw material 公开/授权日:2006-12-21
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