A compressed digital audio signal is transmitted from an audio source along a connection wire to an audio receiver. The digital audio signal can encode digital audio data having different sampling frequencies, frames sizes, and other information. The audio receiver that receives the digital audio signal can decode and convert the compressed digital audio signal into multiple synchronized analog signals, which are used to drive multiple speakers. The audio receiver may also synchronize the audio data with associated video data so that the audio playback and video playback are “in sync”, despite delay introduced by the audio signal decoding at the audio receiver.