发明授权
- 专利标题: Luminescent metal complexes for monitoring renal function
- 专利标题(中): 用于监测肾功能的发光金属络合物
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申请号: US11572920申请日: 2005-08-03
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公开(公告)号: US07674902B2公开(公告)日: 2010-03-09
- 发明人: Raghavan Rajagopalan , Richard B. Dorshow , Dennis A. Moore
- 申请人: Raghavan Rajagopalan , Richard B. Dorshow , Dennis A. Moore
- 申请人地址: US MO St. Louis
- 专利权人: Mallinckrodt Inc.
- 当前专利权人: Mallinckrodt Inc.
- 当前专利权人地址: US MO St. Louis
- 代理机构: Thompson Hine LLP
- 国际申请: PCT/US2005/027486 WO 20050803
- 国际公布: WO2006/026038 WO 20060309
- 主分类号: C07D471/00
- IPC分类号: C07D471/00
摘要:
Some embodiments of the present invention may be said to be directed to metal complexes of Formula I, wherein at least one of X1, X2, X3, R1, R2, R3, R4 and R5 is what may be characterized as an antenna capable of providing (e.g., absorbing and/or emitting) an appropriate electromagnetic signal. Some embodiments of the present invention are directed to ligands corresponding to metal complexes of Formula I. Some embodiments of the invention are directed to methods of determining renal function using at least one metal complex of Formula I.
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