- 专利标题: Hepatocyte growth factor receptor splice variants and methods of using same
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申请号: US11781905申请日: 2007-07-23
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公开(公告)号: US07678769B2公开(公告)日: 2010-03-16
- 发明人: Galit Rotman , Merav Beiman , Michal Ayalon-Soffer , Zurit Levine , Chen Hermesh , Anat Oren , Zohar Tiran , Dvir Dahary , Liat Mintz , Hanqing Xie
- 申请人: Galit Rotman , Merav Beiman , Michal Ayalon-Soffer , Zurit Levine , Chen Hermesh , Anat Oren , Zohar Tiran , Dvir Dahary , Liat Mintz , Hanqing Xie
- 申请人地址: IL Tel Aviv
- 专利权人: Compugen, Ltd.
- 当前专利权人: Compugen, Ltd.
- 当前专利权人地址: IL Tel Aviv
- 代理机构: Fennemore Craig, P.C.
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/00
摘要:
Novel polypeptides that are splice variants of c-Met, the receptor for hepatocyte growth factor and polynucleotides encoding same are provided. Methods and pharmaceutical compositions which can be used to treat various disorders such as cancer, immunological-related, blood-related and skin-related disorders using the polypeptides and polynucleotides of the present invention, are also provided.
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