Invention Grant
- Patent Title: 1,6 naphthyridines useful as inhibitors of SYK kinase
- Patent Title (中): 可用作SYK激酶抑制剂的1,6-萘啶
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Application No.: US12014190Application Date: 2008-01-15
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Publication No.: US07678911B2Publication Date: 2010-03-16
- Inventor: Charles L. Cywin , Scott E. Jakes , Joachim Heider , Mark A. Bobko , Renee L. Des Jarlais , Mark Player , James Rinker , Michael Winters , Bao-ping Zhao
- Applicant: Charles L. Cywin , Scott E. Jakes , Joachim Heider , Mark A. Bobko , Renee L. Des Jarlais , Mark Player , James Rinker , Michael Winters , Bao-ping Zhao
- Applicant Address: US CT Ridgefield
- Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
- Current Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
- Current Assignee Address: US CT Ridgefield
- Agent Michael P. Morris; Mary-Ellen M. Devlin; David L. Kershner
- Main IPC: C07D471/02
- IPC: C07D471/02 ; C07D413/00
Abstract:
Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
Public/Granted literature
- US20080114024A1 1,6 NAPHTHYRIDINES USEFUL AS INHIBITORS OF SYK KINASE Public/Granted day:2008-05-15
Information query
