A micro-spray cooling system for a plurality of heat sources includes an evaporator contacting the heat sources and comprising a plurality of actuators corresponding to the heat sources, a condenser connected to the evaporator, and at least one driving circuit connected to the actuators to drive some or all of the actuators sequentially according to a predetermined timing to cool the heat sources. The refrigerant in the evaporator is sprayed by the actuators to thermally contact the heat sources, evaporated by heat from the heat sources, condensed in the condenser and re-enters the evaporator.