Invention Grant
US07691565B2 Binding molecules for human factor VIII and factor VIII-like proteins
有权
人因子VIII和因子VIII样蛋白的结合分子
- Patent Title: Binding molecules for human factor VIII and factor VIII-like proteins
- Patent Title (中): 人因子VIII和因子VIII样蛋白的结合分子
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Application No.: US11345031Application Date: 2006-01-31
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Publication No.: US07691565B2Publication Date: 2010-04-06
- Inventor: Jinan Yu , M. Daniel Potter , Brian D. Kelley , Jeffrey S. Deetz , James E. Booth
- Applicant: Jinan Yu , M. Daniel Potter , Marilous Potter, legal representative , Brian D. Kelley , Jeffrey S. Deetz , James E. Booth
- Applicant Address: US MA Cambridge
- Assignee: Dyax Corp.
- Current Assignee: Dyax Corp.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi, LLP
- Main IPC: C12Q1/70
- IPC: C12Q1/70
Abstract:
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
Public/Granted literature
- US20060193829A1 Binding molecules for human factor VIII and factor VIII-like proteins Public/Granted day:2006-08-31
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