发明授权
- 专利标题: Reducing myelin-mediated inhibition of axon regeneration
- 专利标题(中): 减少髓鞘介导的轴突再生抑制
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申请号: US11958632申请日: 2007-12-18
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公开(公告)号: US07691590B2公开(公告)日: 2010-04-06
- 发明人: Zhigang He , Kevin C. Wang , Vuk Koprivica , Jieun A. Kim
- 申请人: Zhigang He , Kevin C. Wang , Vuk Koprivica , Jieun A. Kim
- 申请人地址: US MA Boston
- 专利权人: Children's Medical Center Corporation
- 当前专利权人: Children's Medical Center Corporation
- 当前专利权人地址: US MA Boston
- 代理商 Richard Aron Osman
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; G01N33/68 ; G01N33/58 ; G01N33/577
摘要:
Oligodendrocyte-myelin glycoprotein (OMgp)-specific binding agents are used to reduce OMgp-mediated axon growth inhibition. Mixtures of axons and OMgp and mixtures of Nogo receptor (NgR) and OMgp are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to OMgp and promoting axon regeneration.
公开/授权文献
- US20080188411A1 Reducing Myelin-Mediated Inhibition of Axon Regeneration 公开/授权日:2008-08-07
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