Invention Grant
US07695931B2 Carotenoid hydroxylase gene, method for preparing hydroxylated carotenoid, and novel geranylgeranyl pyrophosphate synthase
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类胡萝卜素羟化酶基因，羟基化类胡萝卜素的制备方法和新型香叶基香叶基焦磷酸合成酶
- Patent Title: Carotenoid hydroxylase gene, method for preparing hydroxylated carotenoid, and novel geranylgeranyl pyrophosphate synthase
- Patent Title (中): 类胡萝卜素羟化酶基因，羟基化类胡萝卜素的制备方法和新型香叶基香叶基焦磷酸合成酶
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Application No.: US10579338Application Date: 2004-11-04
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Publication No.: US07695931B2Publication Date: 2010-04-13
- Inventor: Yasuhiro Nishida , Kyoko Adachi , Hiroaki Kasai , Yoshikazu Shizuri , Sadao Komemushi , Norihiko Misawa
- Applicant: Yasuhiro Nishida , Kyoko Adachi , Hiroaki Kasai , Yoshikazu Shizuri , Sadao Komemushi , Norihiko Misawa
- Applicant Address: JP Tokyo
- Assignee: Kirin Holdings Kabushiki Kaisha
- Current Assignee: Kirin Holdings Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch LLP
- Priority: JP2003-388165 20031118; JP2004-165919 20040603
- International Application: PCT/JP2004/016297 WO 20041104
- International Announcement: WO2005/049643 WO 20050602
- Main IPC: C12P23/00
- IPC: C12P23/00 ; C12N9/02 ; C12N1/20 ; C12N15/74 ; C12P21/06 ; C12P19/34 ; C07H21/04
Abstract:
The present invention provides a Brevundimonas sp. strain SD212-derived peptide having β-ionone ring-2-hydroxylase activity and a gene encoding the same, to thereby make it possible to produce rare carotenoids in which a hydroxyl group is introduced at the position 2(2′) carbon in their β-ionone ring in large quantities.The present invention also provides a novel gene encoding an enzyme which introduces a hydroxyl group at the position 3(3′) carbon in the β-ionone ring of carotenoids, and a novel gene encoding a geranylgeranyl pyrophosphate synthase.
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