发明授权
US07700090B2 Co-culture of placental stem cells and stem cells from a second source
有权
来自第二来源的胎盘干细胞和干细胞的共培养
- 专利标题： Co-culture of placental stem cells and stem cells from a second source
- 专利标题（中）： 来自第二来源的胎盘干细胞和干细胞的共培养
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申请号： US11648802申请日： 2006-12-28
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公开(公告)号： US07700090B2公开(公告)日： 2010-04-20
- 发明人: Mohammad Heidaran , Jia-Lun Wang , Qian Ye , Andrew Zeitlin , Colleen Suzanne Dulaney
- 申请人： Mohammad Heidaran , Jia-Lun Wang , Qian Ye , Andrew Zeitlin , Colleen Suzanne Dulaney
- 申请人地址： US NJ Warren
- 专利权人： Anthrogenesis Corporation
- 当前专利权人： Anthrogenesis Corporation
- 当前专利权人地址： US NJ Warren
- 代理机构： Jones Day
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; A61K35/50
摘要：
The present invention relates to a combination of placental stem cells and stem or progenitor cells derived from a second source, wherein the combination shows improved engraftment as compared to placental stem cells or stem cells from a second source, alone. The combination is referred to as a combined stem cell population. The invention also provides in vitro and in vivo methods for identifying and producing combined stem cell populations, and models of engraftment. In accordance with the present invention, the placental stem cells may be combined with, e.g., umbilical cord blood-derived stem or progenitor cells, fetal or neonatal stem cells or progenitor cells, adult stem cells or progenitor cells, hematopoietic stem cells or progenitor cells, stem or progenitor cells derived from bone marrow, etc.
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