发明授权
- 专利标题： Marker for prenatal diagnosis and monitoring
- 专利标题（中）： 产前诊断和监测的标记
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申请号： US11144951申请日： 2005-06-03
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公开(公告)号： US07709194B2公开(公告)日： 2010-05-04
- 发明人: Yuk Ming Dennis Lo , Rossa Wai Kwun Chiu , Stephen Siu Chung Chim , Yu-kwan Tong , Chunming Ding
- 申请人： Yuk Ming Dennis Lo , Rossa Wai Kwun Chiu , Stephen Siu Chung Chim , Yu-kwan Tong , Chunming Ding
- 申请人地址： CN Shatin, New Territories, Hong Kong
- 专利权人： The Chinese University of Hong Kong
- 当前专利权人： The Chinese University of Hong Kong
- 当前专利权人地址： CN Shatin, New Territories, Hong Kong
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12Q1/68
摘要：
The present invention relates to new methods for diagnosing a pregnancy-associated disorder by analyzing fetal DNA present in the mother's blood. More specifically, this invention relies on the discovery that the maspin gene is differentially methylated in fetal DNA and in maternal DNA and provides these new diagnostic methods, which distinguish fetal DNA from maternal DNA and detect prenatal disorders based on abnormalities in fetal DNA level and methylation status.
公开/授权文献
- US20060019278A1 Marker for prenatal diagnosis and monitoring 公开/授权日：2006-01-26
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