发明授权
- 专利标题: Models for vaccine assessment
- 专利标题(中): 疫苗评估模型
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申请号: US11819335申请日: 2007-06-27
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公开(公告)号: US07709257B2公开(公告)日: 2010-05-04
- 发明人: John G. Tew , Mohey Eldin M. El Shikh , Inderpal Singh , Eric Mishkin , Donald Drake, III , Haifeng Song , William L Warren
- 申请人: John G. Tew , Mohey Eldin M. El Shikh , Inderpal Singh , Eric Mishkin , Donald Drake, III , Haifeng Song , William L Warren
- 申请人地址: US FL Orlando US VA Richmond
- 专利权人: Vax Design Corp.,Virginia Commonwealth University
- 当前专利权人: Vax Design Corp.,Virginia Commonwealth University
- 当前专利权人地址: US FL Orlando US VA Richmond
- 代理机构: Roylance, Abrams
- 主分类号: C12N5/00
- IPC分类号: C12N5/00 ; C12N5/02 ; C12N5/16
摘要:
The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.
公开/授权文献
- US20080008653A1 Models for vaccine assessment 公开/授权日:2008-01-10
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