A tower ionizer air cleaner is provided. The tower ionizer air cleaner includes a tower chassis, with a base of the tower chassis including a small footprint, one or more airflow inlet openings in the tower chassis, one or more airflow outlet openings in the tower chassis and substantially opposite to the one or more airflow inlet openings, and an ionizer element positioned within the tower chassis. The tower ionizer air cleaner further includes one or more fan units substantially vertically located within the tower ionizer air cleaner and affixed to the tower chassis. The one or more fan units are configured to provide an airflow between the one or more airflow inlet openings and the one or more airflow outlet openings and through the ionizer element.