发明授权
US07713942B2 Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
失效
包含用于递送多核苷酸的固醇和皂苷的笼状微粒复合物
- 专利标题： Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
- 专利标题（中）： 包含用于递送多核苷酸的固醇和皂苷的笼状微粒复合物
-
申请号： US10114957申请日： 2002-04-04
-
公开(公告)号： US07713942B2公开(公告)日： 2010-05-11
- 发明人: Kristian Dalsgaard , Nikolai Søren Kirkby
- 申请人： Kristian Dalsgaard , Nikolai Søren Kirkby
- 申请人地址： DK Bagsvaerd
- 专利权人： Nordic Vaccine Technology A/S
- 当前专利权人： Nordic Vaccine Technology A/S
- 当前专利权人地址： DK Bagsvaerd
- 代理机构： Sterne, Kessler, Goldstein & Fox, P.L.L.C.
- 优先权： DK200100560 20010404
- 主分类号： A01N43/04
- IPC分类号： A01N43/04 ; A61K31/70 ; A61K9/14 ; A61K45/00 ; A61K47/44
摘要：
The present invention pertains to complexes comprising sterols and saponins. The complexes are capable of binding a genetic determinant including a polynucleotide. The complexes may further comprise a lipophilic moiety, optionally a lipophilic moiety comprising a contacting group and/or a targeting ligand, and/or a saccharide moiety. The complexes may further comprise an immunogenic determinant and/or an antigenic determinant and/or a medicament and/or a diagnostic compound. The complexes may in even further embodiments be encapsulated by an encapsulation agent including a biodegradable microsphere. The present invention also pertains to pharmaceutical compositions and methods of treatment of an individual by therapy and/or surgery, methods of cosmetic treatment, and diagnostic methods practised on the human or animal body.
公开/授权文献
信息查询
IPC分类:
