发明授权
- 专利标题： Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels
- 专利标题（中）： 可靠地达到可接受的血清睾酮水平的方法和药物组合物
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申请号： US10798780申请日： 2004-03-12
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公开(公告)号： US07718640B2公开(公告)日： 2010-05-18
- 发明人: Doris Hubler , Sabine Fricke , Jan-Peter Ingwersen , Wilhelm Kuhnz
- 申请人： Doris Hubler , Sabine Fricke , Jan-Peter Ingwersen , Wilhelm Kuhnz
- 申请人地址： DE Berlin
- 专利权人： Bayer-Schering Pharma AG
- 当前专利权人： Bayer-Schering Pharma AG
- 当前专利权人地址： DE Berlin
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 主分类号： A61K31/56
- IPC分类号： A61K31/56
摘要：
The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.
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