发明授权
- 专利标题: RNAi modulation of ApoB and uses thereof
- 专利标题(中): ApoB的RNAi调节及其用途
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申请号: US12400744申请日: 2009-03-09
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公开(公告)号: US07723317B2公开(公告)日: 2010-05-25
- 发明人: Juergen Soutschek , Hans-Peter Vornlocher , Philipp Hadwiger , Sayda Elbashir
- 申请人: Juergen Soutschek , Hans-Peter Vornlocher , Philipp Hadwiger , Sayda Elbashir
- 申请人地址: US MA Cambridge
- 专利权人: Alnylam Pharmaceuticals, Inc.
- 当前专利权人: Alnylam Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Fenwick & West LLP
- 主分类号: A61K31/71
- IPC分类号: A61K31/71 ; C07H21/02 ; C07H21/04 ; C12Q1/68
摘要:
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.
公开/授权文献
- US20090312397A1 RNAi Modulation Of ApoB And Uses Thereof 公开/授权日:2009-12-17
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