发明授权
- 专利标题: Chromane substituted benzimidazole derivatives
- 专利标题(中): 苯并二氢苯并咪唑衍生物
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申请号: US11612583申请日: 2006-12-19
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公开(公告)号: US07723321B2公开(公告)日: 2010-05-25
- 发明人: Takeshi Hanazawa , Hiroki Koike
- 申请人: Takeshi Hanazawa , Hiroki Koike
- 申请人地址: JP Aichi-Ken
- 专利权人: RaQualia Pharma Inc.
- 当前专利权人: RaQualia Pharma Inc.
- 当前专利权人地址: JP Aichi-Ken
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 主分类号: A61K31/4184
- IPC分类号: A61K31/4184 ; C07D405/02 ; C07D407/02
摘要:
This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5, R6, R7 and R8 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
公开/授权文献
- US20070142448A1 Chromane Substituted Benzimidazole Derivatives 公开/授权日:2007-06-21
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