发明授权
- 专利标题： Antibodies to TGF-β
- 专利标题（中）： TGF-
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申请号： US11350906申请日： 2006-02-08
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公开(公告)号： US07723486B2公开(公告)日： 2010-05-25
- 发明人: Steven R. Ledbetter , Celia P. Hart , Robert G. Holgate , Lutz U. Jermutus , Catriona L. Buchanan , Alexander R. Duncan , Donna K. Finch
- 申请人： Steven R. Ledbetter , Celia P. Hart , Robert G. Holgate , Lutz U. Jermutus , Catriona L. Buchanan , Alexander R. Duncan , Donna K. Finch
- 申请人地址： US DE Wilmington US MA Cambridge
- 专利权人： Optein, Inc.,Genzyme Corporation
- 当前专利权人： Optein, Inc.,Genzyme Corporation
- 当前专利权人地址： US DE Wilmington US MA Cambridge
- 代理机构： Ropes & Gray LLP
- 代理商 Jane T. Gunnison; Z. Ying Li
- 主分类号： C07K16/22
- IPC分类号： C07K16/22 ; C07K14/495
摘要：
The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGFβ1, TGFβ2 and TGFβ3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
公开/授权文献
- US20060251658A1 Antibodies to TGF-beta 公开/授权日：2006-11-09
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