- 专利标题： Treating neurological disorders using selective antagonists of persistent sodium current
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申请号： US11326264申请日： 2006-01-05
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公开(公告)号： US07728034B2公开(公告)日： 2010-06-01
- 发明人: George R. Ehring , Joseph S. Adorante , Larry A. Wheeler , Thomas Malone , Scott M. Whitcup
- 申请人： George R. Ehring , Joseph S. Adorante , Larry A. Wheeler , Thomas Malone , Scott M. Whitcup
- 申请人地址： US CA Irvine
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： US CA Irvine
- 代理机构： Allergan, Inc.
- 代理商 Dean G. Stathakis; Joel B. German
- 主分类号： A01N37/00
- IPC分类号： A01N37/00 ; A61K31/21 ; A01N37/18 ; A61K31/16 ; A01N35/00 ; A61K31/12
摘要：
The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
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