Invention Grant
- Patent Title: Use of TRAIL polypeptides to induce apoptosis
- Patent Title (中): 使用TRAIL多肽诱导细胞凋亡
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Application No.: US12195564Application Date: 2008-08-21
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Publication No.: US07736637B2Publication Date: 2010-06-15
- Inventor: Steven R. Wiley , Raymond G. Goodwin
- Applicant: Steven R. Wiley , Raymond G. Goodwin
- Applicant Address: US WA Seattle
- Assignee: Immunex Corporation
- Current Assignee: Immunex Corporation
- Current Assignee Address: US WA Seattle
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K38/19
- IPC: A61K38/19
Abstract:
A novel cytokine designated TRAIL induces apoptosis of certain target cells, including cancer cells and virally infected cells. Isolated DNA sequences encoding TRAIL are disclosed, along with expression vectors and transformed host cells useful in producing TRAIL polypeptides. Antibodies that specifically bind TRAIL are provided as well.
Public/Granted literature
- US20090118186A1 Use of TRAIL Polypeptides to Treat Cancer Public/Granted day:2009-05-07
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