发明授权
- 专利标题： Antibodies to GM-CSF
- 专利标题（中）： GM-CSF抗体
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申请号： US11672902申请日： 2007-02-08
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公开(公告)号： US07741450B2公开(公告)日： 2010-06-22
- 发明人: Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- 申请人： Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- 申请人地址： US PA Exton
- 专利权人： Morphotek Inc.
- 当前专利权人： Morphotek Inc.
- 当前专利权人地址： US PA Exton
- 代理机构： Woodcock Washburn, LLP
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; C12N5/12
摘要：
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
公开/授权文献
- US20080292641A1 Antigenic GM-CSF peptides and antibodies to GM-CSF 公开/授权日：2008-11-27