发明授权
US07745585B2 Antibodies to interleukin-like epithelial-mesenchymal transition inducer (ILEI)
有权
白细胞介素样上皮间质转化诱导因子(ILEI)
- 专利标题: Antibodies to interleukin-like epithelial-mesenchymal transition inducer (ILEI)
- 专利标题(中): 白细胞介素样上皮间质转化诱导因子(ILEI)
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申请号: US10570448申请日: 2004-09-02
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公开(公告)号: US07745585B2公开(公告)日: 2010-06-29
- 发明人: Andreas Zophel , Horst Johann Ahorn , Birgit Jung , Renate Konopitzky , Karl-Heinz Heider , Norbert Kraut , Peter Seither , Thomas Waerner , Hartmut Beug , Martin Jechlinger , Ido M. Tamir , Andreas Weith , Stefan Gruenert
- 申请人: Andreas Zophel , Horst Johann Ahorn , Birgit Jung , Renate Konopitzky , Karl-Heinz Heider , Norbert Kraut , Peter Seither , Thomas Waerner , Hartmut Beug , Martin Jechlinger , Ido M. Tamir , Andreas Weith , Stefan Gruenert
- 申请人地址: DE Ingelheim
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim
- 代理商 Michael P. Morris; Mary-Ellen M. Devlin; Wendy A. Petka
- 优先权: EP03019551 20030902
- 国际申请: PCT/EP2004/009790 WO 20040902
- 国际公布: WO2005/035762 WO 20050421
- 主分类号: C12P21/08
- IPC分类号: C12P21/08 ; C07K16/00 ; A61K39/395 ; A61K39/00
摘要:
The functional characterization of ILEI to be a novel cytokine involved in epithelial/mesenchymal transition and the identification of biologically active ILEI provides the basis for generating ILEI inhibitors, in particular anti-ILEI antibodies, that are useful in the therapy of cancer, fibrosis and COPD.
公开/授权文献
- US20070089176A1 Cytokine involved in epithelial-mesenchymal transition 公开/授权日:2007-04-19
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