发明授权
- 专利标题: Method of forming a tablet
- 专利标题(中): 形成片剂的方法
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申请号: US11906303申请日: 2007-10-01
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公开(公告)号: US07749537B2公开(公告)日: 2010-07-06
- 发明人: Michael Hite , Cathy Federici , Alan Brunelle , Stephen Turner
- 申请人: Michael Hite , Cathy Federici , Alan Brunelle , Stephen Turner
- 申请人地址: US WA Bellevue
- 专利权人: SCOLR Pharma, Inc.
- 当前专利权人: SCOLR Pharma, Inc.
- 当前专利权人地址: US WA Bellevue
- 代理机构: RatnerPrestia
- 主分类号: A61K9/20
- IPC分类号: A61K9/20 ; A61K31/192
摘要:
A method of forming a tablet includes the steps of pre-blending an active pharmaceutical ingredient susceptible to tackiness and a blending additive with a first mixing effort to form a pre-blend mixture, wherein the first mixing effort and a second mixing effort, resulting from mixing at least one excipient with the pre-blend mixture, form a blend suitable for direct compression and compressing the blend to form the tablet. One way of achieving the first mixing effort is to pre-blend for an extended period of time. The method allows for directly compressing the blend without the need for a granulation step or roller compression. One such active pharmaceutical ingredient susceptible to tackiness is ibuprofen.
公开/授权文献
- US20080131507A1 Method of forming a tablet 公开/授权日:2008-06-05
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