发明授权
- 专利标题： Modification of chemical forces of bone constructs
- 专利标题（中）： 骨构建体化学力的修改
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申请号： US11339781申请日： 2006-01-25
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公开(公告)号： US07749555B2公开(公告)日： 2010-07-06
- 发明人: John M. Zanella , Sean M. Haddock , Catherine E. Taylor , Kathryn J. Kitching
- 申请人： John M. Zanella , Sean M. Haddock , Catherine E. Taylor , Kathryn J. Kitching
- 专利权人： Medtronic, Inc,Warsaw Orthopedic, Inc.
- 当前专利权人： Medtronic, Inc,Warsaw Orthopedic, Inc.
- 主分类号： B05D3/04
- IPC分类号： B05D3/04 ; A61F2/28
摘要：
The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting the binding-sensitized bone graft structure into a host bone; and administering to the binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.
公开/授权文献
- US20070173950A1 Modification of chemical forces of bone constructs 公开/授权日：2007-07-26