发明授权
- 专利标题: Stabilized FGF formulations containing reducing agents
- 专利标题(中): 含有还原剂的稳定的FGF制剂
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申请号: US09944930申请日: 2001-08-31
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公开(公告)号: US07754686B2公开(公告)日: 2010-07-13
- 发明人: Robert V. Hageman , Bret A. Shirley , Kamaljit K. Bajwa
- 申请人: Robert V. Hageman , Bret A. Shirley , Kamaljit K. Bajwa
- 申请人地址: US CA Emeryville
- 专利权人: Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人: Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人地址: US CA Emeryville
- 代理机构: Alston & Bird LLP
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61K38/18 ; C07K14/435 ; C07K14/50
摘要:
Stabilized FGF compositions are provided. The compositions comprise FGF or variant thereof and at least one reducing agent in an amount sufficient to inhibit FGF oxidation. Methods for increasing stability of FGF or variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.
公开/授权文献
- US20080293624A1 Stabilized FGF formulations containing reducing agents 公开/授权日:2008-11-27
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