发明授权
- 专利标题: Process for production of sulfoxide derivatives or salts thereof in the amorphous state
- 专利标题(中): 在非晶状态下生产亚砜衍生物或其盐的方法
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申请号: US11939418申请日: 2007-11-13
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公开(公告)号: US07754887B2公开(公告)日: 2010-07-13
- 发明人: Masahiko Tsujii , Yukio Morita
- 申请人: Masahiko Tsujii , Yukio Morita
- 申请人地址: JP Tokyo
- 专利权人: EISAI R&D Management Co., Ltd.
- 当前专利权人: EISAI R&D Management Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP2003-081261 20030324
- 主分类号: C07D401/12
- IPC分类号: C07D401/12
摘要:
Process for producing sulfoxide derivatives or salts thereof in the amorphous state, characterized by heat-drying solvated crystals of a sulfoxide derivative or a salt thereof represented by the general formula (I): wherein R1 represents a hydrogen atom, a methoxy group, or a difluoromethoxy group; R2 represents a methyl group or a methoxy group; R3 represents a 3-methoxypropoxy group, a methoxy group, or a 2,2,2-trifluoroethoxy group; R4 represents a hydrogen atom or a methoxy group; and B represents a hydrogen atom, an alkali metal or ½ alkaline earth metal.
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