发明授权
- 专利标题： Mass spectrometric methods for detecting mutations in a target nucleic acid
- 专利标题（中）： 用于检测靶核酸突变的质谱法
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申请号： US12125857申请日： 2008-05-22
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公开(公告)号： US07759065B2公开(公告)日： 2010-07-20
- 发明人: Hubert Köster
- 申请人： Hubert Köster
- 申请人地址： US CA San Diego
- 专利权人： Sequenom, Inc.
- 当前专利权人： Sequenom, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Grant Anderson LLP
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34
摘要：
Fast and highly accurate mass spectrometry-based processes for detecting particular nucleic acid molecules and mutations in the molecules are provided. In some embodiments, a process comprises: amplifying one or more target nucleic acid molecules from a biological sample; ionizing and volatilizing the amplified product; and analyzing a product by mass spectrometry to determine an observed molecular mass of the product.
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