Invention Grant
- Patent Title: Mass spectrometric methods for detecting mutations in a target nucleic acid
- Patent Title (中): 用于检测靶核酸突变的质谱法
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Application No.: US12125857Application Date: 2008-05-22
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Publication No.: US07759065B2Publication Date: 2010-07-20
- Inventor: Hubert Köster
- Applicant: Hubert Köster
- Applicant Address: US CA San Diego
- Assignee: Sequenom, Inc.
- Current Assignee: Sequenom, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Grant Anderson LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
Fast and highly accurate mass spectrometry-based processes for detecting particular nucleic acid molecules and mutations in the molecules are provided. In some embodiments, a process comprises: amplifying one or more target nucleic acid molecules from a biological sample; ionizing and volatilizing the amplified product; and analyzing a product by mass spectrometry to determine an observed molecular mass of the product.
Public/Granted literature
- US20090092977A1 MASS SPECTROMETRIC METHODS FOR DETECTING MUTATIONS IN A TARGET NUCLEIC ACID Public/Granted day:2009-04-09
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