发明授权
US07759363B2 Benzimidazole-carboxamide compounds as 5-HT4, receptor agonists
有权
苯并咪唑 - 甲酰胺化合物作为5-HT4受体激动剂
- 专利标题： Benzimidazole-carboxamide compounds as 5-HT4, receptor agonists
- 专利标题（中）： 苯并咪唑 - 甲酰胺化合物作为5-HT4受体激动剂
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申请号： US11439671申请日： 2006-05-24
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公开(公告)号： US07759363B2公开(公告)日： 2010-07-20
- 发明人: Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess
- 申请人： Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess
- 申请人地址： US CA South San Francisco
- 专利权人： Theravance, Inc.
- 当前专利权人： Theravance, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理商 Jeffrey A. Hagenah; Roberta P. Saxon
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; C07D403/14
摘要：
The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
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