发明授权
- 专利标题: Pyridyl derivatives and their use as therapeutic agents
- 专利标题(中): 吡啶衍生物及其作为治疗剂的用途
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申请号: US10566857申请日: 2004-07-29
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公开(公告)号: US07763618B2公开(公告)日: 2010-07-27
- 发明人: Melwyn Abreo , Daniel F. Harvey , Mikhail A. Kondratenko , Wenbao Li , Rajender Kamboj , Vishnumurthy Kodumuru , Michael D. Winther , Heinz W. Gschwend , Nagasree Chakka , Shifeng Liu , Serguei Sviridov , Shaoyi Sun
- 申请人: Melwyn Abreo , Daniel F. Harvey , Mikhail A. Kondratenko , Wenbao Li , Rajender Kamboj , Vishnumurthy Kodumuru , Michael D. Winther , Heinz W. Gschwend , Nagasree Chakka , Shifeng Liu , Serguei Sviridov , Shaoyi Sun
- 申请人地址: CA Burnaby, British Columbia
- 专利权人: Xenon Pharmaceuticals Inc.
- 当前专利权人: Xenon Pharmaceuticals Inc.
- 当前专利权人地址: CA Burnaby, British Columbia
- 代理机构: Osha • Liang LLP
- 国际申请: PCT/US2004/024542 WO 20040729
- 国际公布: WO2005/011654 WO 20050210
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; C07D241/04 ; C07D295/00
摘要:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein W, V, x, y, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
公开/授权文献
- US20060293308A1 Pyridyl derivatives and their use as therapeutic agents 公开/授权日:2006-12-28
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