System for controlling the operation of a motor vehicle diesel engine in which the supply of fuel to the cylinders is controlled as a function of the pressure of a reference cylinder acquired and a predetermined desired fuel supply value for each cylinder, the supply of fuel to the reference cylinder is slaved to its desired supply value as a function of the pressure acquired, the drive shaft rotation speed generated by the displacement of the piston of the reference cylinder and the drive shaft rotation speed generated by the displacement of the piston of at least one other cylinder are acquired, and the supply of fuel to this at least one other cylinder is actuated as a function of the speeds acquired by slaving the drive shaft rotation speed related to the at least one other cylinder to the drive shaft rotation speed related to the reference cylinder.