Invention Grant
US07767418B2 Polynucleotide encoding a novel TRP channel family member, LTRPC3, and splice variants thereof
有权
编码新型TRP通道家族成员的多核苷酸，LTRPC3及其剪接变体
- Patent Title: Polynucleotide encoding a novel TRP channel family member, LTRPC3, and splice variants thereof
- Patent Title (中): 编码新型TRP通道家族成员的多核苷酸，LTRPC3及其剪接变体
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Application No.: US12152547Application Date: 2008-05-15
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Publication No.: US07767418B2Publication Date: 2010-08-03
- Inventor: Ning Lee , Jian Chen , John N. Feder , Shujian Wu , Liana M. Lee , Michael A. Blanar
- Applicant: Ning Lee , Jian Chen , John N. Feder , Shujian Wu , Liana M. Lee , Michael A. Blanar
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Stephen C. D'Amico
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N15/00 ; C07K1/00 ; C07H21/02
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of LTRPC3 polypeptides, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f, respectively. Also provided are vectors, host cells, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Public/Granted literature
- US20080274505A1 Polynucleotide encoding a novel TRP channel family member, LTRPC3, and splice variants thereof Public/Granted day:2008-11-06
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