Invention Grant
- Patent Title: Imidazotriazines and imidazopyrimidines as kinase inhibitors
- Patent Title (中): 咪唑并嗪和咪唑并嘧啶作为激酶抑制剂
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Application No.: US11942130Application Date: 2007-11-19
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Publication No.: US07767675B2Publication Date: 2010-08-03
- Inventor: Jincong Zhuo , Meizhong Xu , Chunhong He , Colin Zhang , Ding-Quan Qian , Brian Metcalf , Wenqing Yao
- Applicant: Jincong Zhuo , Meizhong Xu , Chunhong He , Colin Zhang , Ding-Quan Qian , Brian Metcalf , Wenqing Yao
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Lahive & Cockfield, LLP
- Agent Brian C. Trinque; Pankaj N. Desai
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D403/04 ; C07D403/14 ; A61K31/53 ; A61K31/5377 ; A61P35/00

Abstract:
The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.
Public/Granted literature
- US20080167287A1 IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS Public/Granted day:2008-07-10
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