Invention Grant
- Patent Title: Truncated proteins as cancer markers
- Patent Title (中): 截断的蛋白质作为癌症标志物
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Application No.: US11446420Application Date: 2006-06-02
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Publication No.: US07767789B2Publication Date: 2010-08-03
- Inventor: George Gorodeski , Ying-Hong Feng , Xin Li
- Applicant: George Gorodeski , Ying-Hong Feng , Xin Li
- Applicant Address: US OH Cleveland US MD Rockville
- Assignee: University Hopitals of Cleveland,The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee: University Hopitals of Cleveland,The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee Address: US OH Cleveland US MD Rockville
- Agency: Medlen & Carroll, LLP
- Main IPC: C07K14/82
- IPC: C07K14/82 ; C12P21/06 ; C07K16/30 ; G01N33/574 ; A61K30/00

Abstract:
Methods/reagents for detecting and/or treating cancers or potential cancers are disclosed. In one embodiment, methods and reagents for detecting truncated forms of P2X7 protein in cells are described. In one embodiment, methods and reagents for increasing the amount and/or activity of full-length P2X7 in cells are described. In one embodiment, methods and reagents for decreasing the amount and/or activity of truncated P2X7 in cells are described.
Public/Granted literature
- US20070020706A1 Truncated proteins as cancer markers Public/Granted day:2007-01-25
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