发明授权
- 专利标题： D-amino acid peptides
- 专利标题（中）： D-氨基酸肽
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申请号： US11640790申请日： 2006-12-18
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公开(公告)号： US07776311B1公开(公告)日： 2010-08-17
- 发明人: William J. McBride , David M. Goldenberg
- 申请人： William J. McBride , David M. Goldenberg
- 申请人地址： US NJ Morris Plains
- 专利权人： Immunomedics, Inc.
- 当前专利权人： Immunomedics, Inc.
- 当前专利权人地址： US NJ Morris Plains
- 代理商 Richard A. Nakashima
- 主分类号： A61K38/08
- IPC分类号： A61K38/08 ; A61K38/16 ; A61K39/00 ; A61K36/395 ; A61K51/10 ; C07K5/02 ; C12P21/08
摘要：
The present invention provides compounds of the formula X—R1-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)—R3(Y)—NR4R5; or R1(X)-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)—R3(Y)—NR4R5, in which X is a hard acid cation chelator, a soft acid cation chelator or Ac-, R1, R2 and R3 are independently selected from a covalent bond or one or more D-amino acids that can be the same or different, Y is a hard acid cation chelator, a soft acid cation chelator or absent, Z is a hard acid cation chelator, a soft acid cation chelator or absent, and A and B are haptens or hard acid cation chelators and can be the same or different, and R4 and R5 are independently selected from the group consisting of hard acid cation chelators, soft acid cation chelators, enzymes, therapeutic agents, diagnostic agents and H. The present invention also provides methods of using these compounds and kits containing the compounds.
公开/授权文献
- US20100202961A1 D-AMINO ACID PEPTIDES 公开/授权日：2010-08-12
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